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Optimization of a gene electrotransfer procedure for efficient intradermal immunization with an hTERT-based DNA vaccine in mice

DNA vaccination consists in administering an antigen-encoding plasmid in order to trigger a specific immune response. This specific vaccine strategy is of particular interest to fight against various infectious diseases and cancer. Gene electrotransfer is the most efficient and safest non-viral gene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Methods Clin Dev
Hauptverfasser: Calvet, Christophe Y, Thalmensi, Jessie, Liard, Christelle, Pliquet, Elodie, Bestetti, Thomas, Huet, Thierry, Langlade-Demoyen, Pierre, Mir, Lluis M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362362/
https://ncbi.nlm.nih.gov/pubmed/26015983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.45
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