Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation

The lymphocyte adaptor protein LNK (also known as SH2B3) is primarily expressed in hematopoietic and endothelial cells, where it functions as a negative regulator of cytokine signaling and cell proliferation. Single-nucleotide polymorphisms in the gene encoding LNK are associated with autoimmune and...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Saleh, Mohamed A., McMaster, William G., Wu, Jing, Norlander, Allison E., Funt, Samuel A., Thabet, Salim R., Kirabo, Annet, Xiao, Liang, Chen, Wei, Itani, Hana A., Michell, Danielle, Huan, Tianxiao, Zhang, Yahua, Takaki, Satoshi, Titze, Jens, Levy, Daniel, Harrison, David G., Madhur, Meena S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362266/
https://ncbi.nlm.nih.gov/pubmed/25664851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76327
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars