Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells

Pluripotent stem cells (PSCs) represent an alternative hematopoietic stem cell (HSC) source for treating hematopoietic disease. The limited engraftment of human PSC–derived (hPSC-derived) multipotent progenitor cells (MPP) has hampered the clinical application of these cells and suggests that MPP re...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Gori, Jennifer L., Butler, Jason M., Chan, Yan-Yi, Chandrasekaran, Devikha, Poulos, Michael G., Ginsberg, Michael, Nolan, Daniel J., Elemento, Olivier, Wood, Brent L., Adair, Jennifer E., Rafii, Shahin, Kiem, Hans-Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2015
Soggetti:
Technical Advance
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362238/
https://ncbi.nlm.nih.gov/pubmed/25664855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79328
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