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Recombinant human CD19L-sTRAIL effectively targets B cell precursor acute lymphoblastic leukemia

Patients with B cell precursor acute lymphoblastic leukemia (BPL) respond well to chemotherapy at initial diagnosis; however, therapeutic options are limited for individuals with BPL who relapse. Almost all BPL cells express CD19, and we recently cloned the gene encoding a natural ligand of the huma...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Uckun, Fatih M., Myers, Dorothea E., Qazi, Sanjive, Ozer, Zahide, Rose, Rebecca, D’Cruz, Osmond J., Ma, Hong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2015
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362237/
https://ncbi.nlm.nih.gov/pubmed/25621496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76610
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