Increased fragmentation of sleep-wake cycles in the 5XFAD mouse model of Alzheimer’s disease

Sleep perturbations including fragmented sleep with frequent night-time awakenings and daytime naps are common in patients with Alzheimer’s disease (AD), and these daily disruptions are a major factor for institutionalization. The objective of this study was to investigate if sleep-wake patterns are...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Sethi, Mansi, Joshi, Shreyas S., Webb, Robin L., Beckett, Tina L., Donohue, Kevin D., Murphy, M. Paul, O’Hara, Bruce F, Duncan, Marilyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361816/
https://ncbi.nlm.nih.gov/pubmed/25637807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.01.035
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