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Double NF1 Inactivation Affects Adrenocortical Function in NF1Prx1 Mice and a Human Patient
BACKGROUND: Neurofibromatosis type I (NF1, MIM#162200) is a relatively frequent genetic condition, which predisposes to tumor formation. Apart from tumors, individuals with NF1 often exhibit endocrine abnormalities such as precocious puberty (2,5–5% of NF1 patients) and some cases of hypertension (1...
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Publicado no: | PLoS One |
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Main Authors: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361563/ https://ncbi.nlm.nih.gov/pubmed/25775093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119030 |
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