The Long Pentraxin PTX3 Promotes Fibrocyte Differentiation

Monocyte-derived, fibroblast-like cells called fibrocytes are associated with fibrotic lesions. The plasma protein serum amyloid P component (SAP; also known as pentraxin-2, PTX2) inhibits fibrocyte differentiation in vitro, and injections of SAP inhibit fibrosis in vivo. SAP is a member of the pent...

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Bibliographic Details
Published in:PLoS One
Main Authors: Pilling, Darrell, Cox, Nehemiah, Vakil, Varsha, Verbeek, J. Sjef, Gomer, Richard H.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361553/
https://ncbi.nlm.nih.gov/pubmed/25774777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119709
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