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TNF-α–stimulated fibroblasts secrete lumican to promote fibrocyte differentiation

In healing wounds and fibrotic lesions, fibroblasts and monocyte-derived fibroblast-like cells called fibrocytes help to form scar tissue. Although fibrocytes promote collagen production by fibroblasts, little is known about signaling from fibroblasts to fibrocytes. In this report, we show that fibr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pilling, Darrell, Vakil, Varsha, Cox, Nehemiah, Gomer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586854/
https://ncbi.nlm.nih.gov/pubmed/26351669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507387112
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