ROLES OF OXIDATIVE STRESS AND THE MINERALOCORTICOID RECEPTOR IN CARDIAC PATHOLOGY IN A RAT MODEL OF METABOLIC SYNDROME

Oxidative stress and the mineralocorticoid receptor (MR) are implicated in the pathogenesis of salt-induced left ventricular (LV) diastolic dysfunction associated with metabolic syndrome (MetS). We recently characterized DahlS.Z-Lepr(fa)/Lepr(fa) (DS/obese) rats, derived from a cross between Dahl sa...

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Détails bibliographiques
Publié dans:Nagoya J Med Sci
Auteurs principaux: TAKAHASHI, KEIJI, MURASE, TAMAYO, TAKATSU, MIWA, MATSUURA, NATSUMI, NAGASAWA, KAI, HATTORI, TAKUYA, WATANABE, SHOGO, MUROHARA, TOYOAKI, NAGATA, KOHZO
Format: Artigo
Langue:Inglês
Publié: Nagoya University 2015
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Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361530/
https://ncbi.nlm.nih.gov/pubmed/25797993
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