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GLUCOCORTICOIDS ACTIVATE CARDIAC MINERALOCORTICOID RECEPTORS IN ADRENALECTOMIZED DAHL SALT-SENSITIVE RATS

We previously showed that selective mineralocorticoid receptor (MR) blockade by eplerenone is cardioprotective in Dahl salt-sensitive (DS) rats. To clarify the consequences of glucocorticoid-mediated MR activation in these animals, we investigated the effects of exogenous corticosterone on blood pre...

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Veröffentlicht in:Nagoya J Med Sci
Hauptverfasser: OHTAKE, MASAFUMI, HATTORI, TAKUYA, MURASE, TAMAYO, TAKAHASHI, KEIJI, TAKATSU, MIWA, OHTAKE, MAYUKO, MIYACHI, MASAAKI, WATANABE, SHOGO, CHENG, XIAN WU, MUROHARA, TOYOAKI, NAGATA, KOHZO
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nagoya University 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345730/
https://ncbi.nlm.nih.gov/pubmed/25129992
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