IL-24 Inhibits Lung Cancer Cell Migration and Invasion by Disrupting The SDF-1/CXCR4 Signaling Axis

BACKGROUND: The stromal cell derived factor (SDF)-1/chemokine receptor (CXCR)-4 signaling pathway plays a key role in lung cancer metastasis and is molecular target for therapy. In the present study we investigated whether interleukin (IL)-24 can inhibit the SDF-1/CXCR4 axis and suppress lung cancer...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Panneerselvam, Janani, Jin, Jiankang, Shanker, Manish, Lauderdale, Jason, Bates, Jonathan, Wang, Qi, Zhao, Yan D., Archibald, Stephen J., Hubin, Timothy J., Ramesh, Rajagopal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361489/
https://ncbi.nlm.nih.gov/pubmed/25775124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122439
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