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Contribution of HIV-1 genomes that do not integrate to the basic reproductive ratio of the virus

Recent experimental data indicate that HIV-1 DNA that fails to integrate (from now on called uDNA) can by itself successfully produce infectious offspring virions in resting T cells that become activated after infection. This scenario is likely important at the initial stages of the infection. We us...

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Bibliographische Detailangaben
Veröffentlicht in:J Theor Biol
Hauptverfasser: Lau, John Wei, Levy, David N., Wodarz, Dominik
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361409/
https://ncbi.nlm.nih.gov/pubmed/25496730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2014.12.004
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