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Pyroptosis, superinfection, and the maintenance of the latent reservoir in HIV-1 infection

A long-lived reservoir of latently infected T cells prevents antiretroviral therapy from eliminating HIV-1 infection. Furthering our understanding of the dynamics of latency generation and maintenance is therefore vital to improve treatment outcome. Using mathematical models and experiments, we sugg...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Wodarz, Dominik, Levy, David N.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476677/
https://ncbi.nlm.nih.gov/pubmed/28630490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04130-9
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