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A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice
BACKGROUND: The effect of protein-based meningococcal vaccines on prevention of nasopharyngeal colonization has been difficult to investigate experimentally because a reliable animal colonization model did not exist. METHODS: Human CEACAM1 transgenic mice, which can be colonized by meningococci, wer...
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| Опубликовано в: : | Vaccine |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361389/ https://ncbi.nlm.nih.gov/pubmed/25662856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.01.057 |
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