A native outer membrane vesicle vaccine confers protection against meningococcal colonization in human CEACAM1 transgenic mice

BACKGROUND: The effect of protein-based meningococcal vaccines on prevention of nasopharyngeal colonization has been difficult to investigate experimentally because a reliable animal colonization model did not exist. METHODS: Human CEACAM1 transgenic mice, which can be colonized by meningococci, wer...

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Vydáno v:Vaccine
Hlavní autoři: Pajon, Rolando, Buckwalter, Carolyn M., Johswich, Kay O., Gray-Owen, Scott D., Granoff, Dan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361389/
https://ncbi.nlm.nih.gov/pubmed/25662856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.01.057
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