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The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing and Alzheimer's disease

Peptidyl-prolyl cis/trans isomerases (PPIases), a unique family of molecular chaperones, regulate protein folding at proline residues. These residues are abundant within intrinsically disordered proteins, like the microtubule-associated protein tau. Tau has been shown to become hyperphosphorylated a...

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Dades bibliogràfiques
Publicat a:J Neurochem
Autors principals: Blair, Laura J., Baker, Jeremy D., Sabbagh, Jonathan J., Dickey, Chad A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361273/
https://ncbi.nlm.nih.gov/pubmed/25628064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13033
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