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Potential synergy between tau aggregation inhibitors and tau chaperone modulators

Tau is a soluble, microtubule-associated protein known to aberrantly form amyloid-positive aggregates. This pathology is characteristic for more than 15 neuropathies, the most common of which is Alzheimer’s disease. Finding therapeutics to reverse or remove this non-native tau state is of great inte...

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Библиографические подробности
Главные авторы: Blair, Laura J, Zhang, Bo, Dickey, Chad A
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979086/
https://ncbi.nlm.nih.gov/pubmed/24041111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt207
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