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Can Structural Features of Kinase Receptors Provide Clues on Selectivity and Inhibition?: A Molecular Modeling Study
Cancer is a complex disease resulting from the uncontrolled proliferation of cell signaling events. Protein kinases have been identified as central molecules that participate overwhelmingly in oncogenic events, thus becoming key targets for anticancer drugs. A majority of studies converged on the id...
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| Publicado no: | J Mol Graph Model |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361267/ https://ncbi.nlm.nih.gov/pubmed/25635590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2014.12.007 |
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