Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters

There is emerging interest in understanding the role of progesterone receptors (PRs) in breast cancer. The aim of this study was to investigate the proliferative effect of progestins and antiprogestins depending on the relative expression of the A (PRA) and B (PRB) isoforms of PR. In mifepristone (M...

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Détails bibliographiques
Publié dans:Int J Cancer
Auteurs principaux: Wargon, Victoria, Riggio, Marina, Giulianelli, Sebastián, Sequeira, Gonzalo R., Rojas, Paola, May, María, Polo, María L., Gorostiaga, María A., Jacobsen, Britta, Molinolo, Alfredo, Novaro, Virginia, Lanari, Claudia
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361264/
https://ncbi.nlm.nih.gov/pubmed/25363551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29304
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