Progesterone Receptor Isoform Ratio: A Breast Cancer Prognostic and Predictive Factor for Antiprogestin Responsiveness

Background: Compelling evidence shows that progestins regulate breast cancer growth. Using preclinical models, we demonstrated that antiprogestins are inhibitory when the level of progesterone receptor isoform A (PR-A) is higher than that of isoform B (PR-B) and that they might stimulate growth when...

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Publicado en:J Natl Cancer Inst
Main Authors: Rojas, Paola A., May, María, Sequeira, Gonzalo R., Elia, Andrés, Alvarez, Michelle, Martínez, Paula, Gonzalez, Pedro, Hewitt, Stephen, He, Xiaping, Perou, Charles M., Molinolo, Alfredo, Gibbons, Luz, Abba, Martin C., Gass, Hugo, Lanari, Claudia
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059180/
https://ncbi.nlm.nih.gov/pubmed/28376177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djw317
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