Colorectal Adenomas Contain Multiple Somatic Mutations That Do Not Coincide with Synchronous Adenocarcinoma Specimens

We have performed a comparative ultrasequencing study of multiple colorectal lesions obtained simultaneously from four patients. Our data show that benign lesions (adenomatous or hyperplastic polyps) contain a high mutational load. Additionally multiple synchronous colorectal lesions show non overla...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Vaqué, José P., Martínez, Nerea, Varela, Ignacio, Fernández, Fidel, Mayorga, Marta, Derdak, Sophia, Beltrán, Sergi, Moreno, Thaidy, Almaraz, Carmen, De las Heras, Gonzalo, Bayés, Mónica, Gut, Ivo, Crespo, Javier, Piris, Miguel A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361059/
https://ncbi.nlm.nih.gov/pubmed/25775023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119946
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars