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Molecular Consequences of Altered Neuronal Cholesterol Biosynthesis
The first dedicated step in de novo cholesterol biosynthesis begins with formation of squalene and ends with the reduction of 7-dehydrocholesterol by 7-dehydrocholesterol reductase (Dhcr7) into cholesterol, which is an essential structural and signaling molecule. Mutations in the Dhcr7 gene lead to...
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| Publicado en: | J Neurosci Res |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360921/ https://ncbi.nlm.nih.gov/pubmed/18951487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21917 |
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