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Molecular Consequences of Altered Neuronal Cholesterol Biosynthesis

The first dedicated step in de novo cholesterol biosynthesis begins with formation of squalene and ends with the reduction of 7-dehydrocholesterol by 7-dehydrocholesterol reductase (Dhcr7) into cholesterol, which is an essential structural and signaling molecule. Mutations in the Dhcr7 gene lead to...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci Res
Hoofdauteurs: Korade, Željka, Kenworthy, Anne K., Mirnics, Károly
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360921/
https://ncbi.nlm.nih.gov/pubmed/18951487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21917
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