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A chromatin activity based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing
Immune cells develop endotoxin tolerance (ET) after prolonged stimulation. ET increases the level of a repression mark H3K9me2 in the transcriptional-silent chromatin specifically associated with pro-inflammatory genes. However, it is not clear what proteins are functionally involved in this process...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360912/ https://ncbi.nlm.nih.gov/pubmed/25502336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6733 |
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