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Tracking donor-reactive T cells: evidence for clonal deletion in tolerant kidney transplant patients
T cell responses to allogeneic major histocompatibility (MHC) antigens present a formidable barrier to organ transplantation, necessitating long-term immunosuppression to minimize rejection. Chronic rejection and drug-induced morbidities are major limitations that could be overcome by allograft tole...
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| Udgivet i: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360892/ https://ncbi.nlm.nih.gov/pubmed/25632034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3010760 |
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