CFH Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye

PURPOSE: Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in people 50 years of age or older in developed countries. The homozygous CC genotype in the complement factor H (CFH) Y402H single nucleotide polymorphism (SNP; rs1061170) is widely recognized as a risk f...

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Publicado no:Mol Vis
Main Authors: Wang, Jay Ching Chieh, Cao, Sijia, Wang, Aikun, To, Eleanor, Law, Geoffrey, Gao, Jiangyuan, Zhang, Dean, Cui, Jing Z., Matsubara, Joanne A.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360164/
https://ncbi.nlm.nih.gov/pubmed/25814824
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