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Synthesis and Structure–Activity Relationship Study of 1-Phenyl-1-(quinazolin-4-yl)ethanols as Anticancer Agents
[Image: see text] A quinazoline derivative PVHD121 (1a) was shown to have strong antiproliferative activity against various tumor-derived cell lines, including A549 (lung), NCI-H460 (lung), HCT116 (colon), MCF7 (breast), PC3 (prostate), and HeLa (cervical) cells with IC(50) values from 0.1 to 0.3 μM...
Guardat en:
| Publicat a: | ACS Med Chem Lett |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical
Society
2015
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360158/ https://ncbi.nlm.nih.gov/pubmed/25815147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5004684 |
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