Genetic knockdown of estrogen receptor-alpha in the subfornical organ augments ANG II-induced hypertension in female mice

The present study tested the hypotheses that 1) ERα in the brain plays a key role in the estrogen-protective effects against ANG II-induced hypertension, and 2) that the subfornical organ (SFO) is a key site where ERα mediates these protective actions. In this study, a “floxed” ERα transgenic mouse...

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Publicat a:Am J Physiol Regul Integr Comp Physiol
Autors principals: Xue, Baojian, Zhang, Zhongming, Beltz, Terry G., Guo, Fang, Hay, Meredith, Johnson, Alan Kim
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
Matèries:
Neural Control
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360069/
https://ncbi.nlm.nih.gov/pubmed/25552661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00406.2014
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