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Genetic knockdown of estrogen receptor-alpha in the subfornical organ augments ANG II-induced hypertension in female mice
The present study tested the hypotheses that 1) ERα in the brain plays a key role in the estrogen-protective effects against ANG II-induced hypertension, and 2) that the subfornical organ (SFO) is a key site where ERα mediates these protective actions. In this study, a “floxed” ERα transgenic mouse...
Enregistré dans:
| Publié dans: | Am J Physiol Regul Integr Comp Physiol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360069/ https://ncbi.nlm.nih.gov/pubmed/25552661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00406.2014 |
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