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P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice
NF-κB induces transcriptional expression of proinflammatory genes and antiapoptotic genes. The two activities of NF-κB remain to be characterized in the mechanism of chronic inflammation in obesity. To address this issue, we inactivated NF-κB in adipose tissue by knocking out p65 (RelA) in mice (F-p...
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| Publicado no: | Am J Physiol Endocrinol Metab |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360014/ https://ncbi.nlm.nih.gov/pubmed/25564477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00532.2014 |
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