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Inhibition of Glyceroneogenesis by Histone Deacetylase 3 Contributes to Lipodystrophy in Mice with Adipose Tissue Inflammation

We have reported that the nuclear factor-κB (NF-κB) induces chronic inflammation in the adipose tissue of p65 transgenic (Tg) mice, in which the NF-κB subunit p65 (RelA) is overexpressed from the adipocyte protein 2 (aP2) gene promoter. Tg mice suffer a mild lipodystrophy and exhibit deficiency in a...

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Detalhes bibliográficos
Main Authors: Zhang, Jin, Henagan, Tara M., Gao, Zhanguo, Ye, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075929/
https://ncbi.nlm.nih.gov/pubmed/21406501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0828
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