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Structure-based identification of functional residues in the nucleoside-2′-O-methylase domain of Bluetongue virus VP4 capping enzyme

Bluetongue virus (BTV) encodes a single capping protein, VP4, which catalyzes all reactions required to generate cap1 structures on nascent viral transcripts. Further, structural analysis by X-ray crystallography indicated each catalytic reaction is arranged as a discrete domain, including a nucleos...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Stewart, Meredith E., Roy, Polly
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359970/
https://ncbi.nlm.nih.gov/pubmed/25834778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.02.001
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