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Bluetongue Virus VP1 Polymerase Activity In Vitro: Template Dependency, Dinucleotide Priming and Cap Dependency

BACKGROUND: Bluetongue virus (BTV) protein, VP1, is known to possess an intrinsic polymerase function, unlike rotavirus VP1, which requires the capsid protein VP2 for its catalytic activity. However, compared with the polymerases of other members of the Reoviridae family, BTV VP1 has not been charac...

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Detalhes bibliográficos
Main Authors: Matsuo, Eiko, Roy, Polly
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216989/
https://ncbi.nlm.nih.gov/pubmed/22110731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027702
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