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Structure based modification of Bluetongue virus helicase protein VP6 to produce a viable VP6-truncated BTV

Bluetongue virus core protein VP6 is an ATP hydrolysis dependent RNA helicase. However, despite much study, the precise role of VP6 within the viral capsid and its structure remain unclear. To investigate the requirement of VP6 in BTV replication, we initiated a structural and biological study. Mult...

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Detalhes bibliográficos
Main Authors: Matsuo, Eiko, Leon, Esther, Matthews, Steve J., Roy, Polly
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169673/
https://ncbi.nlm.nih.gov/pubmed/25128829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.08.028
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