BRCA Genetic Screening in Middle Eastern and North African: Mutational Spectrum and Founder BRCA1 Mutation (c.798_799delTT) in North African

Background. The contribution of BRCA1 mutations to both hereditary and sporadic breast and ovarian cancer (HBOC) has not yet been thoroughly investigated in MENA. Methods. To establish the knowledge about BRCA1 mutations and their correlation with the clinical aspect in diagnosed cases of HBOC in ME...

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Vydáno v:Dis Markers
Hlavní autoři: Laraqui, Abdelilah, Uhrhammer, Nancy, EL Rhaffouli, Hicham, Sekhsokh, Yassine, Lahlou-Amine, Idriss, Bajjou, Tahar, Hilali, Farida, El Baghdadi, Jamila, Al Bouzidi, Abderrahmane, Bakri, Youssef, Amzazi, Said, Bignon, Yves-Jean
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359853/
https://ncbi.nlm.nih.gov/pubmed/25814778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/194293
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