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BRCA Genetic Screening in Middle Eastern and North African: Mutational Spectrum and Founder BRCA1 Mutation (c.798_799delTT) in North African

Background. The contribution of BRCA1 mutations to both hereditary and sporadic breast and ovarian cancer (HBOC) has not yet been thoroughly investigated in MENA. Methods. To establish the knowledge about BRCA1 mutations and their correlation with the clinical aspect in diagnosed cases of HBOC in ME...

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Detalhes bibliográficos
Publicado no:Dis Markers
Main Authors: Laraqui, Abdelilah, Uhrhammer, Nancy, EL Rhaffouli, Hicham, Sekhsokh, Yassine, Lahlou-Amine, Idriss, Bajjou, Tahar, Hilali, Farida, El Baghdadi, Jamila, Al Bouzidi, Abderrahmane, Bakri, Youssef, Amzazi, Said, Bignon, Yves-Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359853/
https://ncbi.nlm.nih.gov/pubmed/25814778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/194293
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