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Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development

Ionizing radiation is a potent activator of the tumor suppressor gene p53, which itself regulates the transcription of genes involved in canonical pathways such as the cell cycle, DNA repair and apoptosis as well as other biological processes like metabolism, autophagy, differentiation and developme...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Open
Hauptverfasser: Quintens, Roel, Verreet, Tine, Janssen, Ann, Neefs, Mieke, Leysen, Liselotte, Michaux, Arlette, Verslegers, Mieke, Samari, Nada, Pani, Giuseppe, Verheyde, Joris, Baatout, Sarah, Benotmane, Mohammed A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359739/
https://ncbi.nlm.nih.gov/pubmed/25681390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20149969
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