Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development

Ionizing radiation is a potent activator of the tumor suppressor gene p53, which itself regulates the transcription of genes involved in canonical pathways such as the cell cycle, DNA repair and apoptosis as well as other biological processes like metabolism, autophagy, differentiation and developme...

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Bibliographic Details
Published in:Biol Open
Main Authors: Quintens, Roel, Verreet, Tine, Janssen, Ann, Neefs, Mieke, Leysen, Liselotte, Michaux, Arlette, Verslegers, Mieke, Samari, Nada, Pani, Giuseppe, Verheyde, Joris, Baatout, Sarah, Benotmane, Mohammed A.
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359739/
https://ncbi.nlm.nih.gov/pubmed/25681390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20149969
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