Identification of a DNA methylation signature in blood cells from persons with Down Syndrome

Down Syndrome (DS) is characterized by a wide spectrum of clinical signs, which include segmental premature aging of central nervous and immune systems. Although it is well established that the causative defect of DS is the trisomy of chromosome 21, the molecular bases of its phenotype are still lar...

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Vydáno v:Aging (Albany NY)
Hlavní autoři: Bacalini, Maria Giulia, Gentilini, Davide, Boattini, Alessio, Giampieri, Enrico, Pirazzini, Chiara, Giuliani, Cristina, Fontanesi, Elisa, Scurti, Maria, Remondini, Daniel, Capri, Miriam, Cocchi, Guido, Ghezzo, Alessandro, Del Rio, Alberto, Luiselli, Donata, Vitale, Giovanni, Mari, Daniela, Castellani, Gastone, Fraga, Mario, Di Blasio, Anna Maria, Salvioli, Stefano, Franceschi, Claudio, Garagnani, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359691/
https://ncbi.nlm.nih.gov/pubmed/25701644
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