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Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness

Advanced glycation end-products (AGEs) initiate cellular inflammation and contribute to cardiovascular disease in the elderly. AGE can be inhibited by Alagebrium (ALT), an AGE cross-link breaker. Moreover, the beneficial effects of exercise on aging are well recognized. Thus, we investigated the eff...

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Vydáno v:Exp Gerontol
Hlavní autoři: Steppan, Jochen, Tran, Huang, Benjo, Alexandre M., Pellakuru, Laxsmi, Barodka, Viachaslau, Ryoo, Sungwoo, Nyhan, Sineád M., Lussman, Craig, Gupta, Gaurav, White, Anthony R., Daher, Joao P., Shoukas, Artin A., Levine, Benjamin D., Berkowitz, Dan E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359688/
https://ncbi.nlm.nih.gov/pubmed/22569357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2012.04.006
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