Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness

Advanced glycation end-products (AGEs) initiate cellular inflammation and contribute to cardiovascular disease in the elderly. AGE can be inhibited by Alagebrium (ALT), an AGE cross-link breaker. Moreover, the beneficial effects of exercise on aging are well recognized. Thus, we investigated the eff...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Steppan, Jochen, Tran, Huang, Benjo, Alexandre M., Pellakuru, Laxsmi, Barodka, Viachaslau, Ryoo, Sungwoo, Nyhan, Sineád M., Lussman, Craig, Gupta, Gaurav, White, Anthony R., Daher, Joao P., Shoukas, Artin A., Levine, Benjamin D., Berkowitz, Dan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359688/
https://ncbi.nlm.nih.gov/pubmed/22569357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2012.04.006
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