Concise Reviews: Assisted Reproductive Technologies to Prevent Transmission of Mitochondrial DNA Disease

While the fertilized egg inherits its nuclear DNA from both parents, the mitochondrial DNA is strictly maternally inherited. Cells contain multiple copies of mtDNA, each of which encodes 37 genes, which are essential for energy production by oxidative phosphorylation. Mutations can be present in all...

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Dettagli Bibliografici
Pubblicato in:Stem Cells
Autori principali: Richardson, Jessica, Irving, Laura, Hyslop, Louise A, Choudhary, Meenakshi, Murdoch, Alison, Turnbull, Douglass M, Herbert, Mary
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
Soggetti:
Translational and Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359624/
https://ncbi.nlm.nih.gov/pubmed/25377180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1887
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