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Concise Reviews: Assisted Reproductive Technologies to Prevent Transmission of Mitochondrial DNA Disease

While the fertilized egg inherits its nuclear DNA from both parents, the mitochondrial DNA is strictly maternally inherited. Cells contain multiple copies of mtDNA, each of which encodes 37 genes, which are essential for energy production by oxidative phosphorylation. Mutations can be present in all...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Richardson, Jessica, Irving, Laura, Hyslop, Louise A, Choudhary, Meenakshi, Murdoch, Alison, Turnbull, Douglass M, Herbert, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359624/
https://ncbi.nlm.nih.gov/pubmed/25377180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1887
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