Inhibition of TGF-β by a novel PPAR-γ agonist, chrysin, salvages β-receptor stimulated myocardial injury in rats through MAPKs-dependent mechanism

BACKGROUND: Pharmacological stimulation of peroxisome proliferator-activated receptor-gamma (PPAR-γ) has been recognized as a molecular switch in alleviating myocardial injury through modulating oxidative, inflammatory and apoptotic signaling pathways. This study was designed to elucidate the effect...

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Publicado en:Nutr Metab (Lond)
Autores principales: Rani, Neha, Bharti, Saurabh, Bhatia, Jagriti, Tomar, Ameesha, Nag, T C, Ray, Ruma, Arya, Dharamvir Singh
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359541/
https://ncbi.nlm.nih.gov/pubmed/25774203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12986-015-0004-7
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