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Drug sensitivity in cancer cell lines is not tissue-specific

BACKGROUND: Cancer cell lines have a prominent role in the initial stages of drug discovery, facilitating high-throughput screening of potential drugs. However, their clinical relevance remains controversial. FINDINGS: We assess whether drug sensitivity in cancer cell lines is able to discriminate t...

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發表在:Mol Cancer
Main Authors: Jaeger, Samira, Duran-Frigola, Miquel, Aloy, Patrick
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359490/
https://ncbi.nlm.nih.gov/pubmed/25881072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0312-6
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