Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is characterized by limited response to current drug therapies. Here, we report that SC66, a novel AKT inhibitor, reduced cell viability in a dose- and time-dependent manner, inhibited colony formation and induced apoptosis in HCC cells. SC66 treatment led to a reducti...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Cusimano, Antonella, Puleio, Roberto, D'Alessandro, Natale, Loria, Guido R., McCubrey, James A., Montalto, Giuseppe, Cervello, Melchiorre
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2014
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359326/
https://ncbi.nlm.nih.gov/pubmed/25596737
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items