Helicobacter pylori bacteria alter the p53 stress response via Erk-HDM2 pathway

H. pylori infection is the strongest known risk factor for gastric cancer. Inhibition of host tumor suppressor mechanisms by the bacteria underlies the development of this disease. Among the tumor suppressors affected by H. pylori are p53 and E-cadherin, which inhibition has been shown to increase t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bhardwaj, Vikas, Noto, Jennifer M., Wei, Jinxiong, Andl, Claudia, El-Rifai, Wael, Peek, Richard M., Zaika, Alexander I.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359312/
https://ncbi.nlm.nih.gov/pubmed/25605238
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