Helicobacter pylori bacteria alter the p53 stress response via Erk-HDM2 pathway

H. pylori infection is the strongest known risk factor for gastric cancer. Inhibition of host tumor suppressor mechanisms by the bacteria underlies the development of this disease. Among the tumor suppressors affected by H. pylori are p53 and E-cadherin, which inhibition has been shown to increase t...

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Udgivet i:Oncotarget
Main Authors: Bhardwaj, Vikas, Noto, Jennifer M., Wei, Jinxiong, Andl, Claudia, El-Rifai, Wael, Peek, Richard M., Zaika, Alexander I.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359312/
https://ncbi.nlm.nih.gov/pubmed/25605238
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