DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study

Radioresistance is still an emerging problem for radiotherapy of oral cancer. Aberrant epigenetic alterations play an important role in cancer development, yet the role of such alterations in radioresistance of oral cancer is not fully explored. Using a methylation microarray, we identified promoter...

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Publicado no:Oncotarget
Main Authors: Lin, Hon-Yi, Hung, Shih-Kai, Lee, Moon-Sing, Chiou, Wen-Yen, Huang, Tze-Ta, Tseng, Chih-En, Shih, Liang-Yu, Lin, Ru-Inn, Lin, Jora M.J., Lai, Yi-Hui, Chang, Chia-Bin, Hsu, Feng-Chun, Chen, Liang-Cheng, Tsai, Shiang-Jiun, Su, Yu-Chieh, Li, Szu-Chi, Lai, Hung-Chih, Hsu, Wen-Lin, Liu, Dai-Wei, Tai, Chien-Kuo, Wu, Shu-Fen, Chan, Michael W.Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359265/
https://ncbi.nlm.nih.gov/pubmed/25460508
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