HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape

Histone deacetylase 2 (HDAC2) is overexpressed or mutated in several disorders such as hematological cancers, and plays a critical role in transcriptional regulation, cell cycle progression and developmental processes. Here, we performed comparative transcriptome analyses in acute myeloid leukemia t...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Conte, Mariarosaria, Dell'Aversana, Carmela, Benedetti, Rosaria, Petraglia, Francesca, Carissimo, Annamaria, Petrizzi, Valeria Belsito, D'Arco, Alfonso Maria, Abbondanza, Ciro, Nebbioso, Angela, Altucci, Lucia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359263/
https://ncbi.nlm.nih.gov/pubmed/25473896
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