PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma

Pyruvate kinase M2 (PKM2) is a member of the pyruvate kinase family. Recent work has defined the “non-metabolic” functions of PKM2. However, the role of PKM2 in HCC remains unclear. To investigate the role of PKM2 in tumor growth, invasion and the prognosis of hepatocellular carcinoma (HCC), PKM2 ex...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Liu, Wei-Ren, Tian, Meng-Xin, Yang, Liu-Xiao, Lin, Yu-Li, Jin, Lei, Ding, Zhen-Bin, Shen, Ying-Hao, Peng, Yuan-Fei, Gao, Dong-Mei, Zhou, Jian, Qiu, Shuang-Jian, Dai, Zhi, He, Rui, Fan, Jia, Shi, Ying-Hong
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359260/
https://ncbi.nlm.nih.gov/pubmed/25514599
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